|
Dilek KAZAN, PhD |
|
Department of Bioengineering, Faculty of Engineering,
Marmara University Goztepe Campus, 34722 Kadikoy-Istanbul-Turkey Tel: + 90 212 3480292 / 724 Fax: + 90 212 3450126 HOME
http://mimoza.marmara.edu.tr/~dkazan/ |
|
|
|
|
|
EDUCATION |
|
YEAR |
DEGREE |
UNIVERSITY |
Area |
|
1979-1983 |
BSc |
Istanbul Technical University |
Chemical Engineering Department |
|
1984-1987 |
MSc |
Boğaziçi Üniversitesi |
Chemical Engineering
Department |
|
1988-1993 |
PhD |
Boğaziçi Üniversitesi |
Chemical Engineering
Department |
|
EMPLOYEMENT |
|
YEAR |
TASK |
FOUNDATION |
|
1984-1993 |
Research Assistant |
Boğaziçi Üniversity,
Chemical Eng. Dept. |
|
1994-2001 |
Seniour Scientist |
TÜBİTAK-GMAE
|
|
2001-2004 |
Assoc. Prof |
Marmara
Un. Eng. Faculty, Chemical Eng. Dept.
|
|
2004-continued |
Professor
|
Marmara
Un. Eng. Faculty, Bioengineering Dept.
|
|
APPOINTMENT |
|
YEAR |
TASK |
FOUNDATION |
|
2012- 2015 |
Head of Department |
Marmara Un. Engineering
Faculty, Bioeng. Dept. |
|
2009- 2012 |
Vice Head of Department |
Marmara Un. Engineering
Faculty, Bioeng. Dept. |
|
2006-2009 |
Vice Dean |
Marmara Un. Engineering
Faculty |
|
2002-2006 |
Vice Head of Department |
Marmara Un. Engineering
Faculty, Chemical Eng. Dept. |
|
2000-2001 |
Member
of Institute Committee
|
TÜBİTAK-MAM-GMBAE
|
|
2002-2003 and 2006-2009 |
Member of Faculty
Committee |
Marmara Un. Engineering
Faculty |
|
RESEARCH INTEREST |
|
||||||||||||||||||||
|
Professor Kazan’s research range from Chemical
Engineering to Bioprocess Engineering. She has carried out collaborative
research work to screen, isolate and characterize extremophiles (especially
halophiles and alkaliphiles) to produce
biomaterials (pharmaceuticals, industrial enzymes and biopolymers) with novel
properties; to purify, characterize and stabilize proteins for industrial
applications; to develop and optimize efficient and sustainable bioprocesses;
and to produce biopolymers for biomedical applications. Her research also
covers proteomics and metabolomics to understand the response of living cells
to extreme conditions. With the knowledge gained from the projects and
research activities performed, her most important mission is to achieve
research activities through using
bioprocess engineering tools within the green chemistry approach to
contribute the creation of sustainable environment and society. |
|
||||||||||||||||||||
|
SELECTED PROJECTS |
|
||||||||||||||||||||
|
Ø Production of Bio-similar
Pharmaceuticals “TUBITAK-KAMAG-1007 Project” (Project Manager; In
collaboration with Prof Dr Eda Tahir Turanlı and Assoc. Prof. Dr. Gizem Dinler
Doğanay/ İstanbul Technical University & with Zeynep Atabat/Atabay Pharmaceutical Company) Ø Production of
Poly(3-hydroxybutyrate) from Novel Bacillus
marmarensis GMBE 72T isolated
from mushroom compost: FEN-C-YLP-080715-0341(Project Manager) Ø Production of fermentable sugars by hydrolyses of
haselnut husk, TUBITAK: 113M053 (Project
Manager) Ø Determination of lipid
profiles of microalgae in order to determine biofuel productivity,
-FEN-A-090512-0162. (Project Manager) Ø Formulation of alkaline protease for liquid
detergent, KOSGEB. (Consultant) Ø Using recycled
protein waste for Oncorhynchus mykiss feed
as an alternative protein source, TUBITAK-TEYDEB.
(Consultant) Ø Production of industrial
enzymes intended for feed industry. TUBITAK: KAMAG-107G246.(Researcher) (In
collaboration with Prof Dr Burhan Arına, Prof Dr Sadık Dinçer and Prof Dr Hatice Korkmaz
Güvenmez/ Çukurova
University; Prof Dr Gaye Öngen/Ege University; Assoc Prof Dr Sevnur Mandacı/
TUBITAK-MAM-GMBE) Ø
Investigation
of the kinetic parameters of Bacillus subtilis SDP1 amylase immobilized on magnetic
alginate gels-FEN-D-280214-0047 (Project Manager) Ø
Immobilization
of lipase on magnetic-nano particles-
FEN-C-YLP-060510-0142-(Project Manager) Ø
Proteomic
Investigation of the adaptation of Halomonas halophila DSMZ4770 at high salt concentration and low
temperatures - FEN-D-040609-0179 Ø
Proteomic
analysis of the metabolic pathways of halophilic
microorganisms and flux analysis - FEN-C-DRP-181208-0286. Ø
Production
of amylase enzyme from agricultural waste using Halomonas sp. isolated from Çamaltı Saltern Area FEN-YLS-290506-0115 Ø Extremophiles as source of natural products
useful for biotechnological applications: Studies of osmoregulation
strategies by engineering tools. TUBITAK: TBAG-110T174.(Project Manager) (In
collaboration with Assoc Prof Annarita
Poli and Prof Barbara Nicolaus/ CNR-ITALY) Ø Proteomic Analyses of
Kidney Transplantation Solutions . TUBITAK:
SBAG-110S103.
(Project Manager at Marmara University) (In collaboration with Prof Dr Abdurrahman Coşkun/ Acıbadem University) Ø Establishment of
Bioremediation Laboratory in the Bioengineering Department. Marmara
University Research Fund Project, FEN-E.-. (Project Manager) Ø Production and
characterization of phytase enzyme for animal feed.
Marmara University Scientific Research Project: FEN-C-DRP-171108-0267. (Project Manager) Ø Establisment of Microbial resource Center Infrastructure for Enzyme Industry in Turkey. T.R.
Prime Ministry State Planning Organisation (DPT), conducted at TUBTAK MRC,
GEBI.
(Project Manager) Ø Investigation of the
effect of environmental conditions on newly isolated halophilic
microorganisms by proteomics. TUBITAK: MAG 104M236. (Project Manager) Ø Production of
alpha-amylase from Halomonas sp. isolated
from Çamaltı Saltern Area
by agricultural waste. Marmara University Scientific Research Project:
FEN-YLS-290506-0115.
(Project Manager) Ø Identification of archaea
isolated from extreme environments in Turkey and extremozymes
of these microorganisms. TUBITAK: TBAG 103T069. (Project Manager) (In collaboration with Dr Aziz Akın Denizci/TUBITAK-MRC-GEBI) Ø Stability, conformational
characterization and biocatalytic applications of
native and modified alkaline proteases purified from alkaliphilic
Bacillus strains. conducted at TUBTAK-MRC, GEBI. TUBITAK: TBAG-U/123 (104T262).(Researcher) (in
collaboration with Prof Francesco Secundo/CNR-Italy) Ø BIOCHIPBOARD (Fungal
enzymes on the production of whitelined chipboard:
technological and economic implications. conducted at TUBTAK-MRC, GEBI (In
collaboration with Prof Candan Tamerler/ITÜ;
Prof Tajelli Keshewards/University
of Westminster, KARTONSAN). EUREKA: E2184. (Coordinator) Ø Isolation and
identification of industrially important protein producing bacteria from
local ecosystems. TUBITAK: GMBAE F990201. (Project Manager) conducted at TUBTAK-MRC, GEBI. Ø Identification of
alkaline protease producing microorganisms from local ecosystems and
production and purification of alkaline protease enzyme. Marmara University
Scientific Research Project: BSE 073/131102. (Project Manager) Ø Traditional and modern
solutions for lactose defficiency in Turkey:
Production and development of lactase enzyme used in milk industry, YUUP-DPT
(T.R. Prime Ministry State Planning Organisation BAP-08-11-DPT 2005K120570. (Project Manager at Marmara University Site) (In
collaboration with Prof Şebnem Harsa/
İzmir Institute of Technology) Ø Determination of
anti-viral, anti-microbial and anti-oxidant activity of whey proteins and hydrolysates and determination of structural properties.
TUBITAK: SBAG.
(Manager at Marmara University Site)( In collaboration with Prof Süha Yalçın/Marmara University
and Prof Nazlı Arda/İstanbul
University) Ø Sub-Project 2.2 Penicillin
Acylase Production in “Biotechnology-Establishment and Promotion of New
Biotechnological Techniques in Turkey (NATO-TU BIOTECHNOLOGY)” NATO-SFS
(TUBİTAK-MAM-GMBAE) (Researcher) conducted at TUBTAK-MRC,
GEBI. BSc
Projects (TUBITAK-2209) Ø Investigation of the
inactivation kinetics of Bacillus
licheniformis BA17 alkalen protease at different pH values (MURAT ÖZKAN,
Chemical Engineering Department) Ø Optimization of Phenol
Removal using Halomonas sp. AAD12
(Fatma Ece Altınışık, Bioengineering Department) |
|
||||||||||||||||||||
|
PATENT |
|
||||||||||||||||||||
|
Kayaman, N.,
Kazan, D., Erarslan,
A., Okay, O., Baysal, B., “Application Number: TR96 / 00295, Production
of Temperature Sensitive Gel Beads for Concentrating Dilute solutions of
Biological Materials” T.C. Turkish patent Institute, Acception
date: 03/01/1997. |
|
||||||||||||||||||||
|
PUBLICATIONS |
|
||||||||||||||||||||
Ø Sayar, N.A., Pinar, O., Kazan, D. Sayar, A.A. (2017) Bioethanol Production From Turkish Hazelnut
Husk Process Design and Economic Evaluation., Waste Biomass Valorization. https://doi.org/
10.1007/s12649-017-0103-y
Ø Pinar, O., Karaosmanoğlu, K., Sayar, N.A. Kula. C., Kazan, D., Sayar, A.A. (2017). Assessment of hazelnut
husk as a lignocellulosic feedstock for the
production of fermentable sugars and lignocellulolytic
enzymes.,
3 Biotech, 7:
367. https://doi.org/10.1007/s13205-017-1002-4
Ø
Sahin, Y.M., Su, S., Ozbek, B., Yücel, S., Pinar, O.,
Kazan,D.,
Oktar, F.N., Ekren,
N., Gunduz, O. (2017) Production and characterization of electrospun
fish sarcoplasmic protein based nanofibers.
Journal of food engineering. https://doi.org/10.1016/j.jfoodeng.2017.11.013 Ø
Dilara Ayyildiz, Kazim Yalcin Arga, Fatma Gizem Avci,
Fatma Ece Altinisik, Caglayan Gurer, Gizem Gulsoy Toplan, Dilek Kazan, Katharina Wozny,
Britta Brügger,
Bulent Mertoglu, Berna Sariyar Akbulut (2017). Transcriptomic analysis displays the effect of (-)-roemerine on the motility and nutrient uptake in Escherichia
coli. Curr Genet. DOI 10.1007/s00294-016-0673-4 Ø
Nilay Budeyri Gokgoz, Fatma Gizem Avci,
Kubra Karaosmanoglu Yoneten,
Begum Alaybeyoglu, Elif Ozkirimli, Nihat Alpagu Sayar, Dilek Kazan, and Berna Sariyar Akbulut (2016).
Response of Escherichia coli to Prolonged Berberine
Exposure. Microbial Drug Resistance. DOI: 10.1089/mdr.2016.0063 Ø
Coskun,
A., Baykal, A.T., Kazan, D., et al. Proteomic Analysis of Kidney Preservation
Solutions Prior to Renal Transplantation (2016). PLOS ONE, accepted for
publication. Ø
Kori, M, Aydın, B., Unal,
S., Arga, K.Y., Kazan, D., (2016) Metabolic
Biomarkers and Neurodegeneration: A Pathway Enrichment Analysis of
Alzheimer's Disease, Parkinson's Disease, and Amyotrophic Lateral Sclerosis,
OMICS A Journal of Integrative Biology, 20 (11), DOI: 10.1089/omi.2016.0106 Ø
Bal, E., Pinar, O., Kazan, D., Ozturk, H.U., Sayar, A.A.,
(2016) Immobilization of alpha-amylase from Bacillus subtilis SDP1 isolated from the Rhizosphere of Acacia cyanophila
Lindey, Electronic Journal of Biology, 12:2,
115-121. Ø
Ceylan,S.,Kazan,D., (2015) Pyrolysis kinetics and thermal
characteristics of microalgae Nannochloropsis oculata and Tetraselmis sp., Bioresource Technology. 187, 7 / 2015,
10.1016/j.biortech.2015.03.081 Ø
Öztürk,
H.U. , Sariyar Akbulut,
B. , Ayan, B. , Poli, A.
, Denizci, A.A. , Utkan,
G. , Nicolaus, B., Kazan, D. (2015) Moderately Halophilic
Bacterium Halomonas sp. AAD12: A Promising
Candidate as a Hydroxyectoine Producer. J Microb Biochem Technol., 7,
262-268, http://dx.doi.org/10.4172/1948-5948.1000222 Ø
Dilgimen,
A.S., Arga, K.Y., Erdmann, V.A., Wittmann-Liebold, B., Denizci,
A.A. and Kazan, D. (2014) Comparison of Protein Expression Profiles of Novel Halomonas smyrnensis AAD6Tand
Halomonas
salina DSMZ 5928T. Natural Science, 6, 628-640. http://dx.doi.org/10.4236/ns.2014.69062 Ø
Sayar,
N.A., Durmaz-Sam, S., Kazan, D., Sayar, A.A., (2014) Schizosaccharomyces
pombe and its Ni(II)-insensitive mutant
GA1in Ni(II) uptake from aqueous solutions: a biodynamic model, Appl Microbiol Biotechnol, DOI 10.1007/s00253-014-5740-5 Ø
Duman, Y., Kazan, D., Denizci, A.A., Erarslan, A., (2014) Water Miscible Mono Alcohols’ Effect
on the Proteolytic Performance of Bacillus clausii
Serine Alkaline Protease, Appl Biochem
Biotechnol, 172, 469-486, DOI 10.1007/s12010-013-0525-3 Ø
Poli, A., Nicolaus, B., Denizci,
A.A., Yavuzturk, B., Kazan, D., (2013)
Halomonas smyrnensis sp. nov., a moderately halophilic, exopolysaccharide-producing bacterium from Çamaltı Saltern Area,
Turkey Int J Syst EvolMicrobiol, 63, 10-18 ijs.0.037036-0;, doi: 10.1099/ijs.0.037036-0 Ø
Öztürk, N.C., Kazan, D., Denizci,
A.A., Erarslan, A., (2012) The influence of copper on alkaline protease stability toward
autolysis and thermal inactivation, Eng. Life Sci., 12, No. 5, 1–10 1 Ø
Ceylan, S.,
Yilan, G., Sarıyar-Akbulut,
B., Kazan, D., (2012) Interplay of adaptive capabilities of halomonas sp. AAD12 under salt stress. J. Bioscience and Bioeng. In press Ø
Uzyol K.S., Sarıyar-Akbulut, B., Denizci,
A.A., Kazan, D., (2012) Thermostable
alpha amylase from moderately halophilic Halomonas sp. AAD21. Turk. J. Biol., doi:10.3906/biy-1106-7. Ø
Ceylan,S., Sarıyar-Akbulut, B., Denizci,
A.A., Kazan, D., (2011) Proteomic insight into phenolic adaptation of a
moderately halophilic Halomonas sp.
Strain AAD12. Can. J. Microbiol., 57: 295-302 Ø
Ozbalci, C.,
Unsal, C.,Kazan,
D., Sarıyar-Akbulut, B., (2010) Proteomic Responses
of Esherichia coli to the
alkaloid extract of Papaver polychaetum. Ann Microbiol,
60: 709-717 Ø
Denizci A.A.,
Kazan D., Erarslan .A., (2009) Bacillus
marmarensis sp. nov.,
an alkaliphilic, protease-producing bacterium
isolated from mushroom compost., IJSEM., doi:ijs.0.012369-0 Ø
Oturk, D.,
Kazan, D., Denizci, A.A., Grimoldi,
D., Secundo, F., Erarslan,
A., (2009) Water Miscible Mono Alcohols Effect on the Structural
Conformation of Bacillus clausii GMBAE 42 Serine
Alkaline Protease,Journal of Molecular Catalysis B:
Enzymatic doi:10.1016/j.molcatb.2009.02.017 Ø
Öztürk, S.,
Morgan-Özeren, M., Salman-Dilgimen,A.,
Denizci, A.A.,S Arıkan,
B., Kazan, D., (2009) Alkaline serine protease from halotolerant Bacillus
licheniformis BA17, Annals
Microbiology, 59 (1) 1-8 Ø
Kazan D., Bal H., Denizci A.A.,
Ozturk N.C., Ozturk U., Dilgimen A.S.,
Ozturk D.C., Erarslan .A., STUDIES
ON ALKALINE SERINE PROTEASE PRODUCEDBY Bacillus clausii GMBE
22, Preparative Biochemistry and Biotechnology, Accepted for publication,
ISSN: 1082-6068 print/1532-2297 online, DOI: 10.1080/10826060902953269 Ø
Sarıyar, B.,
Dilgimen Salman, A., Ceylan,
S., Perk, S., Denizci, A., Kazan, D., RAPID
METABOLOME ANALYSIS: Preliminary phenotypic characterization of newly
isolated microorganisms by footprinting, Archieves Microbiology, 2008, 189, 19-26 Ø
Yagız, F.,
Kazan, D., Akin, N.A., Biodiesel production from waste oils by using lipase
immobilized on hydrotalcite and
zeolites, Chemical Engineering Journal Volume 134, Issues
1-3, 1 November 2007, Pages 262-267 Ø
Ates, O., Toksoy Oner,
E., Arıkan, B., Denzci,
A.A., Kazan, D., (2007) Isolation And Identification Of Alkaline
Protease Producer Halotolerant Bacillus licheniformis Strain BA17, Annals Microbiology,
57 (3),369-375 Ø
Kazan, D., Denizci, A., Kerimak, Ö.M.N., Erarslan, A.,
“Purification and characterization of a serine alkaline protease from Bacilllus clausii GMBAE42”
J.Ind. Microbiol
Biotechnology, 32, 335-344 (2005) Ø
Denizci, A., Kazan, D., Abeln, E. C. A., Erarslan, A., Newly ısolated Bacillus
clausii GMBAE42: an alkaline protease
producer capable to grow under higly alkaline
conditions”, Applied Microbiology and Biotechnology, Journal of Applied
Microbiology,96, 320-327
(2004) Ø
Cokuner Öztürk, D., Kazan, D., Erarslan, A., Stabilization and functional properties
of Esherichia coli penicillin
G acylase by cocalent
conjugation of anionic polisaccaride carboxymethylcellulase, World Journal of Microbiology and
Biotechnology,18,
881-888(2002) Ø
Ercelen, S., Kazan, D., Erarslan, A., Demchenko, A.P., On the exiced-state
energy transfer between tryptophan residues in proteins: the case of
penicillin acylase, Biophysical Chenmistry,
90, 203-217
(2001) Ø
Kazan, D., Erarslan, A., The identification of catalytically
essential amino acid residues of penicillin G acylase
obtained from a mutant of Esherichia
coli ATCC 11105, Process Biochemistry, 36, 861-867, (2001) Ø
Kazan, D., Erarslan, A., Effect of dextrans
polymers on the stability of soluble Escherichia coli penicillin
G acylase., J. Chem. Tech. Biotech.,74, 1157-1164,
(1999) Ø
Kayaman, N.,Kazan, D., Erarslan, A., Okay, O., Structure and protein separation
efficiency of poly(N-isopropylacrylamide) gels:
Effect of synthesis conditions., J. Appl. Polymer Sci., 67, 805-814, (1998). Ø
Kazan, D., Ertan, H., Erarslan, A.,
Stabilization of Escherichia coli penicillin G acylase against thermal inactivation by cross-linking
with dextran-dialdehyde polymers.,
Appl. Microbiol. Biotechnol., 48, 191-197,
(1997). Ø
Ertan, H., Kazan, D., Erarslan, A., Cross-linked
stabilization of Escherichia coli penicillin G acylase against pH by dextran-dialdehyde
polymers., Biotechnology Techniques, 11, 225-229,
(1997). Ø
Kazan, D., Erarslan, A., Stabilization of Escherichia coli penicillin
G acylase by polyethylene glycols against thermal inactivation., Appl. Biochem. Biotechnol.,
62, 1-13,
(1997). Ø
Kazan, D., Erarslan, A., Influence of polyhydric compounds on the pH
stability of penicillin G acylase obtained from a
mutant of Escherichia coli ATCC 11105., Process
Biochemistry, 31, 691-697,
(1996). Ø
Kazan, D., Ertan, H., Erarslan, A., Stabilisation of penicillin G acylase
against pH by chemical cross-linking., Process Biochemistry, 31, 135-140,
(1996). Ø Kazan, D., Çamurdan, A., and Hortaçsu, A., The Effect of Glucose Concentration on the
Growth Rate and some Intracellular Components of a Recombinant Escherichia
coli Culture., Process Biochemistry, 30, 269-273, (1995) OTHER PUBLICATIONS Ø
Coskuner Ozturk, D., Erarslan’ A., Kazan, D. “Esherichia coli penisislin asilazının
CMC konjugasyonuyla pH stabilizasyonu” İTÜ Dergisi, Fen Bilimleri, 1, 3-10, 2002 Ø Kazan, D., Ceylan,
S., Unal, S., A. Alp Sayar,
“Tarımsal Atıklardan Biyoetanol Üretimi” Biyoyakıt Dünyası, Sayı:1,
73-74, 2006 |
|
||||||||||||||||||||
|
PRESENTATIONS AT INTERNATIONAL
CONGRESS / SYMPOSIUMS |
|
||||||||||||||||||||
|
Ø Altinisik, F.E., Kazan
D. , B. Sariyar Akbulut. Adaptation of B. marmarensis Sp Nov To Extreme Alkaline Conditions.
7th Congress of European Microbiologists (FEMS),9-13 July 2017, Valencia,
Spain Ø A.Uras, O.Pinar, A.Sayar, D.Kazan, A.A.Sayar. Growth
Medium Optimization of Cryptococcus albidus D24 lipase by statistical design of experiments.
42nd FEBS CONGRESS: FROM MOLECULES TO CELLS AND BACK, 10-14 September 2017
Jerusalem, Israel Ø Su, S., Ozbek,
B., Sahin, Y.M., Yucel,
S., Kazan, D., Oktar,
F.N., Ekren, N., Gunduz,
O., Process Optimization of Electrospun Fish
Sarcoplasmic Protein Based Nanıfibers., Barcelona, Spain., 17-18 August 2017 Ø
Yilmaz-Serçinoğlu,
Z., Sayar, N.A., Kazan, D. Production of laccase and cellulases
by pycnoporus sanguineus
(dmsz 3024) using hazelnut husk .FEMS 2017 - 7th Congress of
European Microbiologists (FEMS), 9-13 Temmuz 2017,
Valencia, İspanya Ø
Abdussamed, U., Sayar, N.A., Kazan, D., Sayar’
A.A. (2016). Immobilization of Cryptococcus albidus D24 Lipase for enzymatic esterification. FEBS, 283 Ø
Tugba’ Ö., Gülnihal,
B., Şirin’ B.,
Çimenoğlu’
Ç., (2016). Utiization
of PHB from Bacillus marmarensis GMBE 72T DSMZ21297 as scaffold. FEBS, 283 Ø Kaplan Coban, E., Gencoğlu, C., Kirman,
D.C., Pinar, O., ,Denizci, A.A., Kazan, D., Sayar,
A.A. (2015). Assessment of the effects
of medium composition on growth lipid accumulation and lipid profile
of Chlorella vulgaris as a biodiesel feedstock. 4th International Conference on Renewable
Energy Research and Applications Ø Altinisik FE, Avci FG, Denizci AA, Kazan D,
Sariyar Akbulut B. Investigation of the proteom profile
of alkaliphilic
B. marmarensis
sp nov under different pH conditions.
FEBS-IUBMB WORKSHOP – Biointeractomics Sevilla-Spain, May 17-20, 2016. Ø Ayyıldız, D., Avcı, F.G., Arga, K.Y., Budeyri Gokgoz, N., Sayar, N.A., Kazan, D., Wozny, K., Bruegger, B., Sariyar Akbulut, B. The plant derived alkaloid roemerine is involved in the modulation of motility in Escherichia coli. The 60th Annual Meeting of the Biophysical Society. 27 February – 2 March 2016 Los Angeles, CA-USA. Ø Yılmaz Z., Pinar
O., Sayar N. A., Kazan D. (2015). Optimization of
process parameters for enzymatic hydrolysis of hazelnut husk. BEC 2015 VII.
Bioengineering Congress, 19-21 November 2015, İzmir-Turkey. Ø Ozgoren, T., Pinar, O., H.U., Kazan,
D., (2015) Response of the Bacillus marmarensis GMBE 72T to extrem conditions: Poly(3hydroxybutyrate), FEBS Journal
282 (Suppl.1) (2015) 55;
Special Issue: 40th FEBS Congress,
The Biochemical Basis of Life, Berlin, Germany, July 4-9, 2015 Ø Ozgoren, T., Pinar,
O., Denizci, A.A., Utkan,
G., Kazan, D., Effect of Different Carbon Sources on the Production of Poly(3-hydroxybutyrate)
, PHB from Bacillus marmarensis GMBE 72T,
BEC 2015 VII. Bioengineering Congress, 19-21 November 2015, İzmir-Turkey Ø Bal, E., Ozturk,
H.U., Kazan, D., (2014) Investigation of the kinetic parameters of
extracellular alpha-amylase from Bacillus subtilis
SDP1 immobilised on alginate beads, ProtStab2014,
10th International Congference on
Protein Stabilization, 7-9 May 2014, Stresa, Italy Ø Budeyri Gokgoz, N., Wozny, K., Kazan,
D., Brügger, B., Sariyar Akbulut, B. Getting
an insight into the antibacterial activity of the
plant derived alkaloid (-)-roemerine against E. coli cells. 39th FEBS-EMBO Conference. 30 August-4 Septemeber, 2014 Paris, France. Ø Karaosmanoğlu K, PİNAR O, SAYAR N.A, Kazan D, (2013) Hydrolysis of Hazelnut Husk by Using Commercial Enzymes for the Production of Fermentable Sugar, 6th International Bioengineering Congress (BEC2013), 12 – 15 November, 2013,Aydın-Turkey. Ø Ozturk H. U, Denizci A.A., Utkan G., Kazan, D., (2013) Application of magnetic alginate beads in both in bioseperation and immobilization of Bacillus subtilis SDP1 α-amylase,Nano TR9, 24-28 Haziran
2013, Erzurum Ø Başak Koçhan, Berna Sarıyar Akbulut, Prof. Dr. Dilek Kazan. Investigation of Osmoadaptation Strategy of a New Moderately Halophilic Halomonas smyrnensis AAD6T
Industrial Biotechnology: meeting the challenges. 12-13 September 2013, Medicon Village, Lund, Sweden. Ø Budeyri Gokgoz, N, Kazan,
D., Sariyar Akbulut, B. Deciphering the antimicrobial alkaloid action on E. coli TB1. ICSB2013, The 14th International Conference on
Systems Biology. 30
AUGUST - 3 September 2013, Copenhagen. Ø Coskun, D. Kazan, M. Akgoz, A. T. Baykal, I. Berber,G. Bilsel3, M. O. Senal, K. Karaosmanoglu, I. Aksoy and C. Yazici, Proteomic evaluation of preservation solutions prior to kidney transplantation, FEBS JOURNAL, Volume 279, pp: 235, Issue Supplement s1,Special Issue: 22nd IUBMB & 37th FEBS Congress, Seville, Spain, September 4-9, 2012 Ø Ayan, B. Sariyar Akbulut and D. Kazan, Growth and osmolyte distribution of a moderately halophilic
microorganism in the presence of phenol, FEBS
JOURNAL, Volume 279, pp: 268, Issue Supplement s1,Special
Issue: 22nd IUBMB & 37th FEBS Congress, Seville, Spain, September 4-9,
2012 Ø N. Budeyri, D. Kazan and B. S. Akbulut,
Investigation of the antimicrobial effect of an alkaloid from Papaver rhoeas K,
FEBS JOURNAL, Volume 279,
pp: 252, Issue Supplement s1,Special Issue: 22nd IUBMB & 37th FEBS
Congress, Seville, Spain, September 4-9, 2012 Ø
Burak Ayan, Berna Sariyar
Akbulut, Annarita Poli, Umit Ozturk,
Nurcin Celik Ozturk, A. Akin Denizci, Guldem Utkan, Dilek Kazan Osmoadaptation of a moderately halophilic
microorganisms under cold stress, New Biotechnology, Volume 29, Supplement, Pages
S55 (23–26 September 2012) Ø
Yonca Avcı Duman, Hatice
Korkmaz, Burhan Arikan, Sadık Dinçer, A. Akın Denizci, Berna Sarıyar Akbulut, Dilek Kazan, Altan Erarslan Purification and characterization of a thermo and
acid-stable endo-1,3-1,4-β-glucanase
from Bacillus amyliquefaciens YMNg47, New
Biotechnology, Volume 29, Supplement, Pages S-80-81 (23–26 September 2012) Ø Melis S. Sogut, Nurcin C. Ozturk, H. Umit Ozturk, Orkun Pinar, Fatih M. Ipek, Ebru Cayir,
Abdulmecit Gokce, Deniz Karasu, Dilek C. Ozturk, Yavuz Ozturk, A. Akin Denizci, Bengu Ozturk, Banu Bahar, Naze G. Avci, Burak Ayan,
Dilek Kazan, Yonca A. Duman, Sayit Sargin, Sevket Karacanli, Cengizhan Mizrak, et al.Production of industrial enzymes for feed
industry New
Biotechnology, Volume 29, Supplement, Pages S108 (23–26 September 2012) |
|
||||||||||||||||||||
|
|||||||||||||||||||||
|
Ø Kazan, D., Mikroorganizma
Kaynak Merkezleri ve Ülkemiz için
Önemi, VI. Ulusal Moleküler Biyoloji ve Biyoteknoloji Kongresi 05-07 Ekim 2017 Çukurova Üniversitesi Adana
(Invited Speaker) Ø Kazan, D. “Mikrobiyal
Mühendislikte Proteomik Yaklaşımlar” "2. Ulusal Proteomik Kongresi – TuPA 2017 24 – 25 Kasım
2017, Acıbadem Ün.,
İstanbul (Invited speaker) Ø Gülnihal BOZDAĞ, Zeynep Efsun DUMAN, Tilbe GÖKÇE, Dilek KAZAN. Gıda atıklarının alternatif olarak kullanımı: Komagataeibacter hansenii DSM
5602 ile bakteriyal selüloz üretimi. VI. Ulusal Moleküler Biyoloji ve Biyoteknoloji Kongresi 05-07 Ekim 2017 Çukurova Üniversitesi Adana Ø Özgören, T., Pinar, O., Bozdağ.
G., Denizci, A.A., Utkan,
G., Kazan, D.
(2016). PHB kaynağı
Bacillus marmarensis GMBE 72T DSM 21297 . VI. Ulusal Polimer Bilim ve Teknolojisi Kongresi |
|
||||||||||||||||||||
|
|||||||||||||||||||||
|
Ø Kazan, D. “Enzim
Mühendisliği’nde Temel Konular ve Uygulamalar” Lisans Üstü Yaz Okulu Kurs
Kitabı ” Ø Kazan, D. “ İmmobilize Enzimler ve Uygulamaları” Lisans Üstü Eğitim Kursu Kurs Kitabı” |
|
||||||||||||||||||||
|
COURSES AND WORKSHOPS ORGANISED |
|
||||||||||||||||||||
|
|
||||||||||||||||||||
|
SUPERVISIONS |
|
||||||||||||||||||||
|
MSc Thesis Ø
Fermentation
of Enzymatically Saccharified Agricultural Residue
for Ethanol Production (Selim Ceylan) Ø
Isolation
and Idendification of Extremophiles Isolated from Camalti Saltern Area (Bahar Yavuzturk) Ø Purification and
Characterization of Alkaline Protease produced by Bacillus sp. Isolated from Local Ecosystems (Selcuk Ozturk) Ø
Productıon
and purification of RTEM-e beta-lactamase ans Its
Inhibition by peptides (Naze Gul Avci’ Co-advisor) Ø
Investigation
of the effect of Antimicrobial Agents on Microorganisms (Çağakan
Özbalcı, Co-advisor) Ø
Amylolytic Enzyme Production from a Moderately Halophilic Bacteria by Using Agricultural Wate (Kamil Serkan
Uzyol) Ø Investigation of
The Kinetics of Bacillus subtilis SDP1 alpha amylase
immobilized on Magnetic Alginate Beads (Eda Bal) Ø Production of Polyhydroxyalkalonate from Extreme Obligate Alkaliphilic Strain Bacillus
marmarensis GMBE 72T isolated from
Mushroom Compost (Tugba Ozgoren) Ø Production of Cellulosic and Polyhydroxybutyrate Based Polymers and Applications in
Tissue Engineering (Gulnihal Bozdag) Ø Small Scale Bioprocess Development and
Immobilization of Lipase from Cryptococcus
albidus (Abdussamed Uras) PhD Thesis Ø
Isolation
and Identification of Industrially Important Protein Producing Bacteria from
Local Ecosystems and Screening of Their Proteins (Hülya Bal) Ø Proteomic Study and Flux Analysis of Metabolic
Pathways of Halophilic Microorganisms (Selim Ceylan) Ø Investigation of the Industrial
Enzymes Produced by Bacillus sp Isolated from Acacia Tree (Hasan Ümit ÖZTÜRK) Ø Investigation of Gene Expression Levels of Newly Isolated Moderately
Halophilic Microorganisms Under Stress Conditions (Serkan Uzyol) Ø Production of Polymeric Nanomaterials
from Renewable Sources for Biomedical Applications (Elif Isikci Koca) |
|
||||||||||||||||||||
|
TEACHING RESPONSIBILITIES |
|
||||||||||||||||||||
|
Undergraduate
Courses General Chemistry Basic Principles in
Chemical Engineering Introduction to
Biochemical Engineering Chemical Kinetics Bioengineering
Principles Bioreaction
Engineering Graduate Courses Reaction Kinetics and
Mass Transfer Enzyme Kinetics Principles in Biotechnology Molecular Techniques
Used for Identification of Microorganisms Enzyme and
Fermentation Technology Proteomics and Mass
Spectrometer Metabolomics Enzyme Technology |
|
||||||||||||||||||||
|
|||||||||||||||||||||
|
Ø Proteom Technologies for Drug Development, 16-17 Mach
2013, KMMO Student Days, İTÜ Ø Biotechnological Applications and potentialities of moderately halophilic
bacteria o Turkish-German Workshop on Biotechnology and
Bioengineering, 21-22 September, 2010, Aachen, Germany o
Proteomic Araştırmaları: Temel Bilgiler ve
Uygulamalı Örnekleri, 10-11 December 2009, Istanbul Ø Biohydrogen Production and Industrial Applications, 14-15 April 2005,
TÜBİTAK, GMBAE Ø Molecular Biology Course, 28 June-09 July 1999, TÜBİTAK, GMBAE |
|
||||||||||||||||||||
|
|
|
||||||||||||||||||||
|
|
|||||||||||||||||||||
|
|||||||||||||||||||||