m-sans-logo-web-color.jpg

image010

MUEF_Logo

 

Personal Web Pages of Academic Staff

Türkçe

 

 

ayfer beceren 3.JPG

 

Assistant Professor Ayfer Beceren (Tozan) 

 

 Contact

 Education

 Professional Experience

 Research Area

 Publications

 Presentations

 Projects

 

 

Contact Information
Ó

 

 

 

E-mail

ayfertozanimage009hotmail.com

ayfer.tozanimage009marmara.edu.tr

 

Phone

+90 216 414 29 62 / 1200

 

Fax

+90 216 345 29 52

 

Correspondence Address

Marmara Üniversitesi Eczacılık Fakültesi

Farmasötik Toksikoloji Anabilim Dalı

Tıbbiye Cad. No. 49  Haydarpaşa  34668  İstanbul

 

Personal web page

http://mimoza.marmara.edu.tr/~ayfer.tozan/

 

 

 

 

Education

Ó

 

 

 

PhD

 

Title

2006 – 2011: Pharmaceutical Toxicology Department

Marmara University Faculty of Pharmacy

Investigation of DNA Damage and DNA Repair Capacity in Patients with Colorectal Cancer and Their First Degree Relatives

 

MSc

 

Title

2003 – 2005: Pharmaceutical Toxicology Department

Marmara University Faculty of Pharmacy

Determination of Diacetoxyscirpenol (Anguidine) in Processed Cereal and Pulse Specimens Provided from Istanbul Market

 

 

BSc

1999 – 2003 : Marmara University Faculty of Pharmacy, İstanbul

 

 

 

 

Professional Experience

Ó

 

 

 

Research Assistant

2003-2012

Marmara University Faculty of Pharmacy, İstanbul                                        

 

Lecturer (PhD)

2012

Marmara University Faculty of Pharmacy, İstanbul                                        

 

Assistant Professor

2012-

Marmara University Faculty of Pharmacy, İstanbul                                        

 

 

 

 

Research Area

Ó

 

 

 

Food Toxicology

Environmental Toxicology

Genetic Toxicology

Oxidative damage and Antioxidants

 

 

 

Publications

Ó

 

 

 

International Journals

 

1

ŞENER, G., OMURTAG, G.Z., ŞEHİRLİ, Ö., TOZAN, A., YÜKSEL, M., ERCAN, F., ve GEDİK, N., “Protective Effects of Ginkgo Biloba Against Acetaminophen-Induced Toxicity In Mice”, Mol. Cell. Biochem., Feb.; 283(1-2), 39-45, (2006).

 

2

TOZAN, A., ŞEHİRLİ, Ö., OMURTAG, G.Z., ÇETİNEL, Ş., CONTUK, G., GEDİK, N. ve ŞENER, G., “Ginkgo biloba extract reduces napthalene-induced oxidative damage in mice”, Phytotherapy Research, 21, 72-77, (2007).

 

3

OMURTAG, G.Z., TOZAN, A., SİRKECİOĞLU, O., KUMBARACI V., ve ROLLAS, S. “Occurrence of Diacetoxyscirpenol (Anguidine) in Processed Cereals and Pulses in Turkey by HPLC”, Food Control, 18(8), 970-974, (2007).

 

4

ŞENER, G., SEHIRLI, Ö., TOZAN, A., VELIOĞLU-ÖVUNÇ, A., GEDIK, N., ve OMURTAG, G.Z., “Ginkgo biloba Extract Protects Against Mercury (II)-Induced Oxidative Tissue Damage in Rats”, Food and Chemical Toxicology, 45(4): 543-550, (2007).

 

5

GÜL, H., OMURTAG, G., ÖNAL, A.E., CLARK, P.M., TOZAN, A., ve ÖZEL, S. “Nonprescription medication purchases and the role of pharmacists as health care workers on self-medication in Istanbul”, Medical Science Monitor, 13(7), PH9-14, (2007).

 

6

SEHIRLI, Ö., TOZAN, A., OMURTAG, G.Z., KESKİNEL, Ş., CONTUK, G., GEDİK, N., and ŞENER, G. ” Protective Effect of Resveratrol Against Naphthalene-Induced Oxidative Stress in Mice”, Ecotoxicol Environ Saf, 71(1), 301-308, (2008)

 

7

OMURTAG, G.Z., TOZAN, A., SEHIRLI, A.Ö., and ŞENER, G. ” Melatonin protects against endosulfan-induced oxidative tissue damage in rats”, Journal of Pineal Research, 44(4), 432-438, (2008).

 

8

GENCOGLU, N., SENER, G., OMURTAG, G.Z., TOZAN, A., USLU, B., ARBAK, S., and, HELVACIOGLU; D. “Comparision of biocompatibility and cytotoxicity of two new root canal sealers” , Acta Histochemica, 112(6):567-75. 2010.

 

9

SARDAS. S., OMURTAG GZ, TOZAN A, GÜL H, BEYOĞLU D. “Evaluation of DNA damage in construction site workers occupationally exposed to welding fumes and solvent based patients in Turkey” , Toxicology and Industrial Health. 26(9): 601–608, 2010.

 

10

SARDAS S, OMURTAG GZ, MONTEIRO IFC, BEYOGLU D, TOZAN-BECEREN A, TOPSAKAL N, COTUK HB. Assessment of DNA Damage and Protective Role of Vitamin E Supplements After Exhaustive Exercise by Comet Assay in Athletes, Journal of Clinical Toxicology, S:5, 2011, http://dx.doi.org/10.4172/2161-0495.S5-001.

 

11

ALTURFAN EI, TOZAN-BECEREN A, SEHIRLI AÖ, DEMİRALP E, ŞENER G, OMURTAG GZ. Protective Effect Of N-Acetyl-L-Cysteine Against Acrylamide-Induced Oxidative Stress In Rats, Turkish Journal of Veterinary And Animal Sciences, 36(4): 438-445,2012.

 

12

ALTURFAN AA, TOZAN-BECEREN AYFER, ŞEHİRLİ AÖ, DEMİRALP E, ŞENER G, OMURTAG GZ. Resveratrol Ameliorates Oxidative DNA Damage and Protects Against Acrylamide-Induced Oxidative Stress in Rats. Molecular Biology Reports. 39(4):4589-96, 2012.

 

 

National Journals

 

1

OMURTAG, G.Z., YAZICIOĞLU, D., BEYOĞLU, D., TOZAN A. ve ATAK, G., “A Review On Fumonisin and Trichothecene Mycotoxins In Foods Consumed In Turkey”, Arı The Bulletin of the Istanbul Technical University, 54(4), 39-44, 2006.

 

2

TOZAN-BECEREN A, OMURTAG GZ, YEĞEN C, ŞARDAŞ S. Investigation of DNA Damage in Patients with Colorectal Cancer and Their First Degree Relatives, Journal of Marmara University Institute of Health Sciences (MÜSBED). 1(3):155-161, 2011.

 

3

TOZAN-BECEREN A, ŞEHİRLİ AÖ, EKSİOGLU-DEMİRALP E, ŞENER G, OMURTAG GZ. Melatonin Protects Against Acrylamide-Induced Oxidative Tissue Damage in Rats. Marmara Pharmaceutical Journal. 16:134-142, 2012.

 

 

 

 

Presentations

Ó

 

 

 

International Scientific Meetings

 

1

GÜL, H., OMURTAG, G.Z., TOZAN, A. ve ÖZDEN, Y., "The Role of Turkish Pharmacists In Health Care: A Research in Province of Istanbul", 10th International Congress of Toxicology (ICTX), Tampere, Finland, Toxicology and Applied Pharmacology , (P-311, 205-206, Poster Bildiri), (11-15 July, 2004).

 

2

GENÇOĞLU, N., ŞENER, G., OMURTAG, G.Z., TOZAN, A., USLU, B. ve ARBAK, S., “Comparison of Biocompatibility and Cytotoxicity of Two New Root Canal Sealers”, Discover your roots, 12th Biennial Congress, The European Society of Endodontology (ese), Dublin, Ireland, (R74, 24, Poster Bildiri), (15-17 September 2005).

 

3

OMURTAG, G.Z. ve TOZAN, A., "Determination of Diacetoxyscirpenol in Food Specimens by HPLC", 8th International Symposium on Pharmaceutical Sciences, Ankara, (P-69, Poster bildiri), (June 13-16, 2006).

 

 

4

ŞEHİRLİ, Ö., TOZAN, A., OMURTAG, G.Z., ÇETİNEL, Ş., CONTUK, G., GEDİK, ve N., ŞENER, G., "Protective Effect Of Resveratrol Against Naphthalene-Induced Oxidative Stress In Mice", 8th International Symposium on Pharmaceutical Sciences, Ankara, (P-70, Poster bildiri), (June 13-16, 2006).

 

5

ŞENER, G., ŞEHİRLİ, Ö., TOZAN, A., VELİOĞLU-ÖVÜNÇ, A., GEDİK, N., ve OMURTAG, G.Z., "Ginkgo biloba Extract Protects Against Mercury (II)-Induced Oxidative Tissue Damage In Rats", 8th International Symposium on Pharmaceutical Sciences, Ankara, (P-67, Poster bildiri), (June 13-16, 2006).

 

6

TOZAN, A., ŞEHİRLİ, Ö., OMURTAG, G.Z., ÇETİNEL, Ş., CONTUK, G., GEDİK, ve N., ŞENER, G., "Protective Effect Of Ginkgo biloba Against Naphthalene-Induced Oxidative Stress In Mice", 8th International Symposium on Pharmaceutical Sciences, Ankara, (P-68, Poster bildiri), (June 13-16, 2006).

 

7

TOZAN, A., OMURTAG, P.S., ve OMURTAG, G.Z. "Determination Of Nivalenol In Corn And Corn Products By HPLC", 6th International Congress of Turkish Society of Toxicology, Antalya, (P-120, Poster Bildiri), (November 2006). 

 

8

ŞENER, G., OMURTAG, G.Z., TOZAN, A., ŞEHİRLİ, A.Ö., DEMİRALP, E., ve GEDİK, N., "Melatonin Ameliorates Acrylamide-Induced Oxidative Stress In Rats", 6th International Congress of Turkish Society of Toxicology, Antalya, (P-146, Poster Bildiri), (November 2-5, 2006).

 

9

OMURTAG, G.Z., TOZAN, A., ŞEHİRLİ, A.Ö., DEMİRALP, E., GEDİK, N., ve ŞENER, G. “Resveratrol Against Acrylamide-Induced Oxidative Stress In Rats6th International Congress of Turkish Society of Toxicology, Antalya, (P-144, Poster Bildiri), (November 2-5, 2006).

 

10

OMURTAG, G.Z., GÜL. H., YAZAR, S., BEYOĞLU, D., TOZAN, A., ŞARDAŞ, S. “DNA Damage Assessment By Comet Assay In Workers Exposed To Welding Fume Metals3RD Euro-Asian Conference on Hazardous Waste & Human Health, Istanbul, (Poster Bildiri), (March 27-30, 2008).s

 

11

BEYOĞLU, D., AKICI, N., OMURTAG, G.Z., ÖZKOZACI, T., TOZAN, A., CERAN, Ö., AKICI, A., ŞARDAŞ, S. “Evaluation of DNA Damage by Chromosomal Aberration and Comet Assay in Children Exposed to Tobacco Smoke3RD Euro-Asian Conference on Hazardous Waste & Human Health, Istanbul, (Poster Bildiri), (March 27-30, 2008).

 

12

OMURTAG, G.Z., GÜL. H., YAZAR, S., BEYOĞLU, D., TOZAN, A., KADIOĞLU, E., and ŞARDAŞ, S. “DNA Damage Comparison Between Construction Site Workers and Controls by Comet Assay“ 10th European Regional Meeting, Vienna, Austria, (Poster Bildiri), (May 18-21, 2008).

 

13

OMURTAG, G.Z., GÜL. H., YAZAR, S., BEYOĞLU, D., TOZAN, A., KADIOĞLU, E., and ŞARDAŞ, S. “DNA Damage Comparison Between Construction Site Workers and Controls by Comet Assay“ 10th European Regional Meeting, Vienna, Austria, (Poster Bildiri), (May 18-21, 2008).

 

14

BECEREN A., OMURTAG G.Z., TOLAN K., SENKESEN Ö., YEGEN C., SARDAS S., Investigation of DNA damage and DNA repair capacity in patients with colorectal cancer and their first degree  relatives. Third International Meeting on Pharmacy & Pharmaceutical Sciences, İstanbul, Turkey, (P-105, Poster Bildiri), (June 9-12, 2010)

 

15

BECEREN A., OGUZ S, OMURTAG G.Z., INANC N, DİRESKENELİ H, SARDAS S., The role of GSTM1 polymorphism in individual susceptibility to rheumatoid arthritis 9th International ISSX Meeting, İstanbul-Turkey (P-LB5, Poster Bildiri), (September 4-8, 2010).

 

16

YESİL T, BECEREN A, SARDAS S. In vivo genotoxicity studies in various occupational settings in Turkey. 9th International Comet Assay Workshop, (ICAW) Kuşadası-Turkey (P-24, Poster Presentation), (September 13-16, 2011)

 

 

17

ŞARDAŞ S, BECEREN A, OMURTAG GZ. Evaluation of DNA damage in various occupations exposed to different chemicals in Turkey. (Oral presentation),   Collegium Ramazzini, October 26-28, Carpi, Italy.

 

18

TOZAN BECEREN A, OMURTAG GZ, YEĞEN C, ŞENKESEN Ö, ŞARDAŞ S. Investigation of DNA damage and DNA repair capacity in patients with colorectal cancer and their first degree relatives. (Oral presentation), 8th Turkish Society of Toxicology Congress,  November 15-18 2012, Antalya- Turkey.

 

19

ŞARDAŞ S, BECEREN A, OMURTAG GZ. Evaluation of DNA damage in various occupations exposed to different chemicals in Turkey. (Oral presentation),   Collegium Ramazzini, October 26-28, Carpi, Italy.

 

National Scientific Meetings

 

1

TOZAN A, OMURTAG GZ. Determination of diacetoxyscirepenol (Anguidin) in cereals and pulses by HPLC", V. National Chromatography Congress, Poster Presentation, P-90, Eskişehir, 30 June-2 July (2004).

 

2

TOZAN A, OMURTAG GZ, ERSOY Ö, Determination of T-2 Toxin in cereals and pulses by HPLC, V. National Chromatography Congress, Poster Presentation, P-109, Eskişehir, 30 June-2 July (2004).

 

3

ŞENER, G., OMURTAG, G.Z., SEHİRLİ, Ö., TOZAN A., YÜKSEL, M., ERCAN, F. ve GEDİK, N.,  The protective effects of Gingko Biloba against toxicity - induced acetominofen in mice. Union of research of antioxidant and free radicals IV.National Chromatography Congress, Poster Presentation, P-7, Larespark Hotel/ Lara-Antalya, 9-12 May(2005).

 

4

OMURTAG, G.Z., YAZICIOĞLU, D., BEYOĞLU, D., TOZAN A., ve ATAK, G.,  Fumonisins and trichothecene in nutritions, 2.National Mycotoxin Symposium, Oral Declarations, 73-79, Eds. HEPERKAN D., KAYA G.D., GÜLER F.K., Mycotoxin Studies in Turkey , II.National Mycotoxin Symposium Declaration Book, İTÜ Kimya- Metallurgy Faculty, Food Engineering Department, İstanbul, 23-25 May (2005).

 

5

GÜL H, OMURTAG G, ÖNAL AE, TOZAN A, ÖZEL S and ÖZDEN YI. Drug consumption with and without receipt and effective factors in Istanbul, 9. National Public Health Days -GATA (Environmental Health), Poster Presenatation P-214, 145, Kızılcahamam-Ankara, 28 September-1 October(2005).

 

6

CONTUK G, TOZAN A, ŞEHİRLİ Ö, OMURTAG GZ, ÇETİNEL Ş, GEDİK N, and ŞENER G. Protective effects of Ginkgo Biloba against napthalene induced damage in mice, VIII. Ulusal Histoloji & Embriology Congree, Poster Presentation, sh.217, 27-30 June 2006, İnönü University, Malatya.

 

7

OMURTAG, G., TOZAN, A., ŞEHİRLİ, Ö., ARBAK, S., TURAN, P., GEDİK, N., and ŞENER, G. Protective effect of N- Acetyl -L- Cyctein and melatonin against endosulfan induced oxidative tissue damage, VIII. National Histology & Embriology Congree, Poster Presentation, sh.228, 27-30 June 2006, İnönü University Malatya.

 

8

CONTUK, G., ŞEHİRLİ, Ö., TOZAN, A., OMURTAG, G.Z., ÇETİNEL, Ş., GEDİK, N., and ŞENER, G. Protective effect of resveratrol against naphthalene enduced damage in mice, VIII. National Histology & Embriology Congree, Poster Presentation, sh.217, 27-30 June 2006, İnönü University, Malatya

 

9

ŞARDAŞ, S., BEYOĞLU, D., AKICI, N., OMURTAG, G.Z., ÖZKOZACI, T., TOZAN, A., CERAN, Ö., AKICI, A.  Determination for DNA damage of children (passive smokers) exposed to tobacco smoking. II. Multidiciplener Cancer Research Symposium, Poster Presentation, Bursa (24-27 February 2008).

 

10

TOZAN, A., TOLAN K., OMURTAG, G.Z., ŞENKESEN Ö., YEĞEN C., ŞARDAŞ S. Investigation of DNA damage and DNA repair capacity in patients with colorectal cancer and their first degree relatives. 7. Uluslararası Katılımlı Türk Toksikoloji Derneği Kongresi, Poster Presentation P-18, Ankara, 30 May-01 June (2009).

 

11

BECEREN A., OMURTAG G.Z., DÖNBAK L., ÇİMEN B., YEŞİL T., ŞARDAŞ S. The Investigation of Genotoxic Damage, on Print Workers using the Alkaline Comet Method. I. International Palandöken Toxicology Symposium, Poster Presentation, Erzurum (28-30 May 2010).

 

 

 

 

Projects

Ó

 

 

 

1

Kolorektal Kanser Tanılı Olgularda ve Birinci Derece Yakınlarında DNA Hasarının ve Onarım Kapasitesinin Araştırılması
M.Ü. Bilimsel Araştırma Projeleri Komisyon Başkanlığı - SAG-C-DRP-030108-0010 Project Participant, 2008- 2011..

 

2

Sigara İçen ve İçmeyen Ebeveynlerin Çocuklarının DNA Hasarı Bakımından Karşılaştırılması.
M.Ü. Bilimsel Araştırma Projeleri Komisyon Başkanlığı - SAG-BGS-060907-0179, Project Participant, 2007-2008.

 

3

Akrilamid’in Neden Olduğu Toksisitede Serbest Radikallerin Rolü ve Bazı Antioksidanların Koruyucu Etkisinin İncelenmesi.
M.Ü. Bilimsel Araştırma Projeleri Komisyon Başkanlığı - SAG-BGS-270605-0133, Project Participant, 2005-2007

 

4

İstanbul’da Piyasadan Temin Edilen İşlenmiş Hububat ve Bakliyat Örneklerinde Diasetoksissirpenol (Anguidin) Aranması ve Miktar Tayini.
M.Ü. Bilimsel Araştırma Projeleri Komisyon Başkanlığı - SAĞ-044/230804, Project Participant, 2004-2005