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Official website of Assoc.Prof. Ş.Güniz Küçükgüzel

 

RESEARCH AREA

 

Research Topics

Design and development of new synthetic compounds in search of better chemotherapeutics against several infectious disease including tuberculosis and AIDS. Research area also covers antibacterial, antifungal agens as well as screening of new compounds synthesized in our labs as  antiinflammatory and anticonvulsant drug candidates.

Design, synthesis and characterization of new compounds as potential dyestuffs.

In vivo metabolism of drug substances and model compounds.

Organic structures and functionalities synthesized :

Hydrazones

1,3-Thiazolidine-4-ones

2-Pyrazolin-5-ones

Isoxazolones

1,3,4-Oxadiazoles

1,2,4-Triazoles

1,3,4-Thiadiazoles

Thioureas

 

 

  Collaborative research done with

TAACF, Southern Research Institute, Alabama, USA

National Institute of Neurological Disorders and Stroke (NINDS), National Institutes of Health (NIH)

Developmental Therapeutics Program (DTP), National Cancer Institute (NCI), National Institutes of Health (NIH)

Department of Biochemistry and Molecular Biology, Center for the Study of Emerging and Re-Emerging Pathogens, UMDNJ-New Jersey Medical School, 185 South Orange Avenue, Newark, NJ 07103, USA

Department of Genetic and Bioengineering, Faculty of Engineering and Architecture, Yeditepe University, İstanbul 34755, Turkey

Biotechnology Application and Research Center, Ataturk University, Erzurum 25240, Turkey