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Doç.Dr. Ş.Güniz Küçükgüzel'in resmi internet sitesi

 

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1.

Kömürcü, Ş.G., S.Rollas, M.Ülgen, J.W.Gorrod, A.Çevikbaş

Evaluation of Some Arylhydrazones of p-Aminobenzoic acid hydrazide as Antimicrobial Agents and Their in-vitro Hepatic Microsomal Metabolism

Boll.Chim.Farmaceutico 134(7), 375-379(1995).

2.

Kömürcü, Ş.G., S.Rollas, N.Yılmaz, A.Çevikbaş

Synthesis of 3-Methyl-4-[(2,4-dihydro-4-substituted-3H-1,2,4-triazole-3-thione-5-yl)phenylhydrazono]-5-isoxazolone and Evaluation of Their Antimicrobial Activities

Drug Metabolism and Drug Interactions 12, 161-169(1995).

3.

Küçükgüzel, Ş.G., S.Rollas, İ.Küçükgüzel, M.Kiraz

Synthesis and Antimycobacterial activity of some coupling products from 4-aminobenzoic acid hydrazones

Eur.J.Med.Chem. 34, 1093-1100 (1999).

4.

Küçükgüzel, Ş.G., S.Rollas, H.Erdeniz, M.Kiraz , A.C.Ekinci, A.Vidin

Synthesis, characterization and pharmacological properties of some 4-arylhydrazono-2-pyrazoline-5-one derivatives obtained from heterocyclic amines

Eur.J.Med.Chem.  35, 761-771 (2000).

5.

Küçükgüzel, Ş.G., İ.Küçükgüzel, M.Ülgen

Metabolic and Chemical Studies on N-(4-chlorobenzyl)-N’-benzoylhydrazine

Farmaco  55, 624-630, (2000).

6.

Küçükgüzel, İ., Ş.G. Küçükgüzel, S. Rollas, M. Kiraz

Some 3-thioxo / alkylthio-1,2,4-triazoles with a substituted thiourea moiety as possible antimycobacterials

Biorg. & Med.Chem. Letters  11, 1703-1707, (2001).

7.

Küçükgüzel, Ş.G., E.E. Oruç, S. Rollas, F.Şahin, A.Özbek

Synthesis, Characterization and biological activity of novel 4-thiazolidinones, 1,3,4-oxadiazoles and some related compounds

Eur.J.Med.Chem.  37, 197-206, (2002).

8.

Küçükgüzel, Ş.G., S.Rollas

Synthesis, Characterization of Novel Coupling Products and 4-Arylhydrazono-2-pyrazoline-5-ones as Potential Antimycobacterial Agents

Farmaco 57, 583-587, (2002).

9.

Ş.Güniz Küçükgüzel, Adil Mazi, Fikrettin Şahin , Suzan Öztürk, James P.Stables

Synthesis and biological activities of diflunisal hydrazide-hydrazones

Eur.J.Med.Chem. 38, 1005-1013, (2003).

10.

İlkay Küçükgüzel , Ş.Güniz Küçükgüzel, Sevim Rollas, Gülten Ötük-Sanış, Osman Özdemir, İbrahim Bayrak, Tuncay Altuğ, James P. Stables

Synthesis of some 3-(arylalkylthio)-4-alkyl/aryl-5-(4-aminophenyl)-4H-1,2,4-triazole derivatives and their anticonvulsant activity

Farmaco  59, 893-901, (2004).

Full text via Science Direct >>

11.

Ş.G.Küçükgüzel, İ. Küçükgüzel, B.Oral, F.S.Sezen, S.Rollas

Detection of nimesulide metabolites in rat plasma and hepatic subcellular fractions by HPLC-UV/DAD and LC-MS/MS studies

Eur.J.Drug Metab.Pharmacokinet. 30, 127-34 (2005).

12.

Ş.Güniz Küçükgüzel , Ayla Kocatepe, Erik De Clercq, Fikrettin Şahin, Medine Güllüce

Synthesis and biological activity of 4-thiazolidinones, thiosemicarbazides derived from diflunisal hydrazide

Eur.J.Med.Chem, in press (2006).

13.

Koçyiğit-Kaymakçıoğlu B., Oruç E.E., Yılmaz-Demircan F., Gürbüz Y., Kalaça S., Küçükgüzel Ş.G., Ülgen M., Rollas S. “A High Performance Liquid Chromatografic Method for the quantification of Cotinine in the ürine of preschool children” Pharmazie, 61(10), 823-827 (2006).

14.

Ş.Güniz Küçükgüzel, İlkay Küçükgüzel, Esra Tatar, Sevim Rollas, Fikrettin Şahin, Medine Güllüce, Erik De Clercq, Levent Kabasakal “Synthesis of some novel heterocyclic compounds derived from diflunisal hydrazide as potential anti-infective and anti-inflammatory agents” Eur.J.Med.Chem, 42, 893-901 (2007).

15.

Sevim Rollas, Ş.Güniz KüçükgüzelBiological Activities of Hydrazone Derivatives” Molecules, 12, 1910-1939, (2007).

16.

Neerja Kaushik-Basu, Alain Bopda-Waffo, Amartya Basu, Ye Chen, Tanaji T. Talele, S.Güniz Küçükgüzel. “4-Thiazolidinones: A Novel Class as Hepatitis C Virus NS5B Polymerase Inhibitors” Fronters in Bioscience, 13, 3857-3868 (2008).

17.

Sevgi Karakuş, İlkay Küçükgüzel, Ş.Güniz Küçükgüzel “Development and validation of a rapid and sensitive RP–HPLC method for the determination of cetirizine or fexofenadine with pseudoephedrine in binary pharmaceutical dosage forms” Journal Biomedical Chromatography 46, 295-302 (2008).

18.

Küçükgüzel İ, Tatar E., Küçükgüzel Ş.G., Rollas S., De Clercq E., “Synthesis of Some novel thiourea derivatives obtained from 5-[(4-aminophenoxy)methyl]-4-methyl-2,4-dihydro-3H-1,2,4-triazole-3-thiones and evaluation as antiviral / anti-HIV agents” Eur.J.Med.Chem, ,43, 381-392 (2008).

19.

Bedia Koçyiğit-Kaymakçıoğlu, Seda Ünsalan, Ş.Güniz Küçükgüzel, Göksel Şener, Sevim Rollas “HPLC-UV/DAD analysis for in vivo metabolites of 4-nitrobenzoic acid[(5-nitro-2-thiophenyl)methylene]hydrazide in rats” Eur J Drug Metab Pharmacokinet. in press (2008).